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Terry W. Hill
Professor of Biology
James T. and Valeria B. Robertson Chair in Biological Sciences
Department of Biology
Office: 110 Frazier Jelke West
e-mail hill@rhodes.edu
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BIOL-130
Introductory Biology
BIOL-201 Mycology
BIOL-307 Cell Biology
BCMB-310 Methods in
Biochemistry and Cell Biology
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Research Colleagues
Link to Former Research Associates
Goals and Projects
The long-term goal of research in this laboratory is to understand how the structural components of fungal cell walls are synthesized, assembled according to specific patterns, and developmentally modified throughout the organism's life. Through a better understanding of the cell wall we may discover keys to better control over growth of economically and medically important fungi.Our principal current projects focus on the role of Protein Kinase C (PKC) in wall metabolism during polarized cell growth in the filamentous fungus Aspergillus nidulans and on the role of the Golgi apparatus in the synthesis and delivery of cell wall constituents to the fungal cell surface.
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Students with strong research interests in cell biology, biochemistry, genetics, or microbiology are encouraged to apply for positions in this lab.Click here for
information on undergrad research |
Jackson-Hayes, L., T. W. Hill, D. M. Loprete, L. M. Fay, B. S. Gordon, S. A. Nkashama, R. K. Patel, and C. V. Sartain. 2008. "Two GDP-mannose transporters contribute to hyphal form and cell wall integrity in Aspergillus nidulans." Microbiology 154: 2037-2047.
Teepe, A. G., D. M. Loprete, Z.-M. He, T. A. Hoggard, and T. W. Hill. 2007. "The protein kinase C orthologue PkcA plays a role in cell wall integrity and polarized growth in Aspergillus nidulans". Fungal Genetics & Biology 44: 554-562.
Hill, T. W., D. M. Loprete, M. Momany, Y. Ha, L. M. Harsch, J. A. Livesay, A. Mirchandani, J. J. Murdock, M. J. Vaughan, and M. B. Watt. 2006. "Isolation of cell wall mutants in Aspergillus nidulans by screening for hypersensitivity to Calcofluor White". Mycologia 98: 400-410.
Momany, M., R. Lindsey, T. W. Hill, E. A. Richardson, C. A. Momany, M. Pedreira, G. M. Guest, J. F. Fisher, R. B. Hessler, and K. A. Roberts. 2004. "The Aspergillus fumigatus cell wall is organized in domains that are remodeled during polarity establishment". Microbiology 150: 3261-3268.
Hill, T. W., D. M. Loprete, J. A. Castagna, and S. O. Weems. 2003. "Efficient high-volume cleaning of Aspergillus nidulans cleistothecia using bare fingers". Fungal Genetics Newsletter 50: 4-5.
Loprete, D. M. and T. W. Hill. 2002. "Isolation and characterization of an endo-(1,4)-b-glucanase secreted by Achlya ambisexualis". Mycologia 94: 903-911.
Hill, T. W., D. M. Loprete, K. N. Vu, S. P. Bayat Mokhtari, and L. V. Hardin. 2002. "Proteolytic release of membrane-bound endo-(1,4)-b-glucanase activity associated with cell wall softening in Achlya ambisexualis". Canadian Journal of Microbiology 48: 93-98.
Hill, T. W. and E. Kafer. 2001. "Improved protocols for Aspergillus minimal medium: Trace element and minimal medium salt stock solutions". Fungal Genetics Newsletter 48: 20-21.
Reichard, U., G. T. Cole, T. W. Hill, R. Rüchel, and M. Monod. 2000.
"Molecular characterization and influence on fungal development of ALP2, a novel
serine proteinase from Aspergillus fumigatus". International Journal of
Medical Microbiology 290: 549-558.
