Terry W. Hill
Professor of Biology
Department of Biology
Link to Former Research Associates
Goals and Projects
The long-term goal of research in this laboratory is to contribute to our understanding of fungal cell development - especially the areas of tip growth and septation.
Our principal current projects focus on the roles played by Protein Kinase C (PKC) and cytoskeletal proteins during polarized cell growth in the filamentous fungus Aspergillus nidulans.
Students with strong research interests in cell biology, biochemistry, genetics, or microbiology are encouraged to apply for positions in this lab.
Jackson-Hayes, L., T. W. Hill, D. M. Loprete, C. DelBove, J. Shapiro, J. Henley, and O. Dawodu. 2015. "Two amino acid sequences direct Aspergillus nidulans protein kinase C (PkcA) localization to hyphal apices and septation sites." Mycologia In Press.
Gremillion, S. K., S. D. Harris, L. Jackson-Hayes, S. G. W. Kaminskyj, D. M. Loprete, A. C. Gauthier, S. Mercer, A. J. Ravita, and T. W. Hill. 2014. "Mutations in proteins of the Conserved Oligomeric Golgi complex affect polarity, cell wall structure, and glycosylation in the filamentous fungus Aspergillus nidulans." Fungal Genetics & Biology 73: 69-82.
Jackson-Hayes, L., T. W. Hill, D. M. Loprete, B. S. Gordon, C. J. Groover, L. R. Johnson, and S. A. Martin. 2010. "GDP-mannose transporter paralogues play distinct roles in Aspergillus nidulans cell wall integrity." Mycologia 102: 305-310.
Jackson-Hayes, L., T. W. Hill, D. M. Loprete, L. M. Fay, B. S. Gordon, S. A. Nkashama, R. K. Patel, and C. V. Sartain. 2008. "Two GDP-mannose transporters contribute to hyphal form and cell wall integrity in Aspergillus nidulans." Microbiology 154: 2037-2047.
Teepe, A. G., D. M. Loprete, Z.-M. He, T. A. Hoggard, and T. W. Hill. 2007. "The protein kinase C orthologue PkcA plays a role in cell wall integrity and polarized growth in Aspergillus nidulans". Fungal Genetics & Biology 44: 554-562.
Hill, T. W., D. M. Loprete, M. Momany, Y. Ha, L. M. Harsch, J. A. Livesay, A. Mirchandani, J. J. Murdock, M. J. Vaughan, and M. B. Watt. 2006. "Isolation of cell wall mutants in Aspergillus nidulans by screening for hypersensitivity to Calcofluor White". Mycologia 98: 400-410.
Momany, M., R. Lindsey, T. W. Hill, E. A. Richardson, C. A. Momany, M. Pedreira, G. M. Guest, J. F. Fisher, R. B. Hessler, and K. A. Roberts. 2004. "The Aspergillus fumigatus cell wall is organized in domains that are remodeled during polarity establishment". Microbiology 150: 3261-3268.
Loprete, D. M. and T. W. Hill. 2002. "Isolation and characterization of an endo-(1,4)-β-glucanase secreted by Achlya ambisexualis". Mycologia 94: 903-911.
Hill, T. W., D. M. Loprete, K. N. Vu, S. P. Bayat Mokhtari, and L. V. Hardin. 2002. "Proteolytic release of membrane-bound endo-(1,4)-β-glucanase activity associated with cell wall softening in Achlya ambisexualis". Canadian Journal of Microbiology 48: 93-98.
Hill, T. W. and E. Kafer. 2001. "Improved protocols for Aspergillus minimal medium: Trace element and minimal medium salt stock solutions". Fungal Genetics Newsletter 48: 20-21.
Reichard, U., G. T. Cole, T. W. Hill, R. Rüchel, and M. Monod. 2000. "Molecular characterization and influence on fungal development of ALP2, a novel serine proteinase from Aspergillus fumigatus". International Journal of Medical Microbiology 290: 549-558.